ONABOTULINUM TOXIN-A FOR OVERACTIVE BLADDER

Botulinum Toxin for an Overactive Bladder

Botulinum toxin A for the Treatment of Overactive Bladder

The standard treatment for overactive bladder starts with patient education and behavior therapies, followed by antimuscarinic agents. For patients with urgency urinary incontinence refractory to antimuscarinic therapy, currently both American Urological Association (AUA) and European Association of Urology (EAU) guidelines suggested that intravesical injection of botulinum toxin A should be of...

Botulinum Toxin – a promising new treatment for overactive bladder

Onabotulinum Toxin A (Botox®) in the Treatment of Neurogenic Bladder Overactivity

Botulinum toxin (BT) is a potent presynaptic neuromuscular blocking agent which induces selective, reversible muscle weakness for months when injected intramuscularly. During recent years BT has revolutionized the treatment of previously intractable symptoms of detrusor overactivity. Based on a systematic search of the PubMed database, a review of the current literature on the use of onabotulin...

Overactive bladder.

Overactive bladder (OAB) is common and has a negative impact on a patient's quality of life. It is important for physicians to know how to identify and manage patients with this condition. Usually only basic clinical evaluations and a good patient history are necessary to diagnose OAB. Effective and safe oral therapy is available and can be initiated by primary care physicians.